

In most cases, most release groups already fine tune encoding settings towards various balances of file size and quality, so the best option is to decide on a set of release group whose standards meet your needs and just use the files as they come without further modification.
Applying lossy compression to a video that’s already had lossy compression applied to it degrades it unnecessarily, so if you’re going to compress it yourself, it’s best to start with the remux, aka the original media file.
I’d personally recommend releases from members of the qxr group and Vyndros.
I imagine it’ll run much better on the Switch 2, given how well it runs on my Steam Deck, though I imagine that it would take a lot of adjustment to get used to using joystick controls versus the touchpad controls of the Steam Deck. Perhaps however the new ‘mouse-like controls’ work will be more helpful in that regard, but I can’t imagine even that would match the precision of a trackpad.
Don’t intend on supporting Nintendo’s crazy price increases myself, and will only get a Switch 2 if a way to hardware mod it becomes available, but I think it’s a bit ironic that the one non-first party game someone would specifically want to play on the Switch is also the one that not only never goes on sale, but also got a price increase.